CARI Jhansi

Research Projects

1. Ongoing and completed research projects .

More than 50 EMR/IMR/Collaborative projects are ongoing. The section wise list is appended below.

Chemistry Section –

• Development of Quality Standards of Noncodified Lead Plants (DST-NIF) (Completed).
• Preclinical Standardization and Development of Standard Operating Procedure for AYUSH Coded Drug SG-5 (Ayush SG-5) (Completed).
• Development of Quality Standards of Ayurvedic Plants for the Ayurvedic Pharmacopoeia of India. (Monograph Development) (Completed).
• Preclinical standardization and Development of SOP for Coated Tablets from Aqueous and Hydroalcoholic Extract of Amlaki, Guduchi and Vasa and Shelf-life Studies (Completed).
• Marker based Shelf-life study and Development of Marker (s) Based Quantification Methods for the Most Valuable Ayurvedic Raw Drugs. (Completed)
• Pre-clinical development of Guduchi (Tinospora cordifolia (Thumb) Miers) stem through AYUSH route for adjunct therapy in tuberculosis to reduce anti-tubercular treatment (ATT) induced hepatotoxicity. (Ongoing)
• Pre-clinical development of Amalaki (Phyllanthus emblica linn.) fruit through AYUSH route for adjunct therapy in tuberculosis to reduce anti-tubercular treatment (ATT) induced hepatotoxicity. (Ongoing)
• Pre-clinical development of Vasa (Justicia adhatoda linn.) Leaves through AYUSH route for adjunct therapy in tuberculosis to reduce anti-tubercular treatment (ATT) induced hepatotoxicity. (Ongoing)
• Development of Quality Standards, Estimation of Markers and Shelf-life Study of Ayush-82 and Ayush-SG. (Ongoing)
• Development of Quality Standards, Estimation of Markers/PRS & Shelf-life Study of CCRAS Coded Drugs AYUSH SDM Tablet and AYUSH PK Avaleha. (Ongoing)
• Development of SoP, QC Standards & Shelf-life Study of CCRAS Coded Drug AYUSH UT Ointment. (Ongoing)
• QC Analysis, Estimation of Markers/PRS & shelf-life Studies of Ayush PVK Gel, Ayush AGT Cream and Ayush AGT Lotion. (Ongoing)
• Effect of geographical variations, phytochemicals profiling and marker-based quantification of selected medicinally important Ficus Species. (Ongoing)
• Marker-based Traceability in Ayush Kwath Churna and its Raw Drugs, Shelf-life and Exploration of Antioxidant & Antimicrobial Potency: A new horizon to explore Ayush Kwath Churna. (Ongoing)
• QC, Analysis, Estimation of Markers /PRS & Shelf – life studies of Ayush PTK and GO-Mutra Haritaki. (Ongoing)
• Development of Drug Master File and Dossier on Fruit of Picrorhiza kurroa an important promising Medicinal Plants Based on leads From Ayurvedic & Contemporary Research. (Ongoing)
• Isolation of Markers Compounds from Ayurvedic Ingredients Used in CCRAS Coded Drugs Namely Ayush-HR, Ayush-56, Ayush-PJ-7 & Ayush-SC-3 etc. (Ongoing)

Pharmacy Section

• Process Standardization of Polyherbal Formulations (Ajmodadi Churna, Panchkola Churna, and Haridradi Churna) with their Shelf-life study and Anti-microbial Activity Evaluation. (Ongoing)
• Formulation Development and Pharmaceutical standardization of Amrutadi Vati (tablets) by different methods using Churna, Aqueous and Hydroalcoholic Estract with their Comparative analytical and Accelerated Stability Studies. (Ongoing)
• Formulation Development, Pharmaceutical Standardization and Accelerated Stability Studies of Pushkar Gugglu Tablets. (Ongoing)
• Process validation, pharmaceuticals standardization of shelf-life and antimicrobial activity of Pippalyadi Yonivarti, Arkadi Yonivarti and Kushthadi Yonivarti. (Ongoing)
• Pharmaceuticals Development and standardization of Ayush VR oil, its Gel/Ointment Form with Accelerated Stability, In-silico, Antibacterial and Antifungal Activities. (Ongoing)
• Process Validation, Pharmaceuticals standardization and evaluation of antimicrobial activity of Ajeernakantak Ras, Kanaksundar Ras and Hinguleshvara Ras. (Ongoing)
• Pharmaceuticals Standardization, Antimicrobial Activity and Accelerated Stability study of Arkas of Ajmodadi Guduchi, Kiratatikta and Mishreya. (Ongoing)
• Identification of adulterants/ substitutes for Ayurveda Plants raw material in trade using pharmacognostic and phytochemicals parameters. (Ongoing)
• Insilico network pharmacology study of selected coded formulation of CCRAS. (Ongoing)
• Preclinical toxicity Study of Dhatri Lauha. (Ongoing)
• Pharmaceutical Standardization and Characterization of Yashad Bhasma Prepared by traditional and contemporary method of heating. (Ongoing)
• Process Validation, Pharmaceuticals Standardization, Accelerated Stability Study and Evaluation of Antimicrobial Activity of Ayush Ghutti Dispersible Tablet. (Ongoing)
• Pharmaceutical Standardization of five Calcium Containing bhasmas (Shankha, Shukti, Varatika, Godanti and Kukkutanda Twak) and their Chemical analysis by Advanced Technical analytical techniques. (Completed)
• Mechanistic studies in Elucidation of Shodhana for nine Poisonous medicinal plants of E1 Schedule. (Ongoing)
• Design and Development of a device for efficient removal and recovery of Heavy metals from the fumes of Rasa Ausadhies during its preparation. (Ongoing)
• Process Validation Pharmaceutical Standardization and accelerated stability study of Ayush LND Tablets. (Completed)
• Profiling of Phytochemical in “Ayurvedic Medicinal Formulation” and understanding their Aggregation Behavior. (Ongoing)

Microbiology Section

• Identification of potent anti-microbial compounds from medicinal plants against multi-drug resistant ESKAPE(E) Bacteria isolated from different water sources in and around Jhansi district (Ongoing)
• In-Vitro Screening of Plants/Vegetables/fruits/Herbs for their suitability as Prebiotics. (Ongoing)
• To investigate the inhibitory effect of various medicinal plants used in the Ayurvedic system against Dental Caries causing Micro-organisms. (Ongoing)
• Characterization of Important Ayurvedic Medicinal Plants through DNA Barcoding. (Ongoing)
• Screening of various herbal/plant based raw materials for fungal growth associated with Mycotoxin Contamination. (Ongoing)

Botany Section

• Anthology of Survey Research outcome from Medico Ethno Botanical Survey (MEBS). (Ongoing)
• A comparative Study on Hydroponic and Field Cultivated Medicinal Plants used in Ayurveda (Ongoing)

Pharmacognosy Section

• Pharmacognosticals Evaluation of Medicinal Plants cited in Ayurvedic Formulary of India excluding the Plants mentioned in Ayurvedic Pharmacopeia of India Part-II. (Ongoing)